Thank you for visiting the Salis research lab at Penn State University. We develop biophysical models and methods to rationally predict and control the behavior of biological organisms. We design, construct, and optimize synthetic genetic systems for biotechnological purposes with applications in synthetic biology, metabolic engineering, and biologic therapeutics.

You can learn more about our research projects or read our publications.

We are also creating a genetic compiler to help you build your own genetic systems.

August 2011 -- Howard presents the labs' work on optimizing a synthetic biodetoxification pathway and rationally designing synthetic small RNAs at the Society for Industrial Microbiology (SIM) annual meeting in New Orleans and at the q-Bio conference on cellular information processing, sponsored by the Los Alamos National Laboratory, in Santa Fe.

July 2011 -- Iman Farasat presents his work on the RBS Library Calculator at the Biochemical and Molecular Engineering XVII conference in Seattle, WA.

June 2011 -- Amin Espah Borujeni presents his work on the Small RNA Calculator at Synthetic Biology v5.0 at Stanford University.

March 2011 -- Howard presents the lab's work on optimizing a synthetic biodetoxification pathway for lignocellulosic hydrolysate at the annual meetings of the Institute of Biological Engineering and the American Chemical Society.

January 2011 -- Amin Espah Borujeni, Iman Farasat, and Jason Collens present their work on the RBS Library Calculator and the Small RNA Calculator at the International Conference on Biomolecular Engineering in San Francisco.

December 2010 -- Tian Tian, Long Chen, and Bayram Bulut have joined the Salis lab as first-year graduate students. Welcome!

June 2010 -- Iman Farasat has received the Leighton Riess Graduate Fellowship in Engineering for outstanding work! Congratulations!

April 2010 -- Howard Salis has received the DARPA Young Faculty Award for the "Rational Design of Nucleic Acids to Control Metabolism and Kill Pathogens".

February 2010 -- Jason Collens, Ph.D. has joined the Salis lab as a postdoctoral fellow! Welcome!

January 2010 -- Amin Espah Borujeni and Iman Farasat have joined the Salis lab as first-year graduate students. Welcome!